SAYPHA® filler


Saypha/Princess 23mg/ml is a sterile, viscoelastic, clear, isotonic and homogenised gel implant.


immediately available

(€48,000.00 per Liter)

Delivery time 2 - 3 days within Germany


Saypha® FILLER (1 x 1ml)

Saypha Filler (formerly Princess) is a universal product suitable for various aesthetic treatments such as correction of moderate facial wrinkles and lines and improvement of lip volume. The product can be used for all areas of the face, especially perioral wrinkles, lip contours and to increase lip volume. It is recommended to inject Saypha® FILLER into the mid to deep dermis to achieve a very natural look and long-lasting correction.

The package consists of:

1 x 1 ml syringe

2 x 27G 1/2 "needles

23 mg / ml sodium hyaluronate

Advantages of Saypha® Filler

By restoring your natural hyaluronic acid levels, Chroma HA fillers help reverse the signs of aging and help you look younger, fresher and more radiant. Hyaluronic filler treatments are non-surgical. They achieve immediate, visible, natural-looking results with minimal downtime.

- Optimal skin compatibility

The use of hyaluronic acid of non-animal origin and Croma's strict safety requirements guarantee a pure and safe product.

- Painless treatment

Most people find hyaluronic filler injections relatively painless. The addition of lidocaine, a mild anesthetic, to certain products makes the injection even more comfortable for you. In addition, Croma HA fillers are inserted into the skin with thin-walled needles specifically designed for optimal patient comfort.

- Satisfied patients

Almost 98% of patients are satisfied with our products and would recommend treatment to their friends.

- Natural results and outstanding efficacy

Clinical studies confirm the effectiveness and long-lasting aesthetic results2 of Croma HA fillers.

- Immediate effect

With Croma Hyaluron fillers you will see immediate, natural results, with no risk of your face looking "frozen", changing or losing your natural facial expressions.

Saypha Hyaluron Filler

Treatment areas of Saypha® Filler

- Can be used in all areas of the face

- Gently correct wrinkles and fine lines

- To compensate for volume loss

- Improve lip volume and shape

- Improve complexion and skin elasticity

- improve the moisture balance of the skin and its overall appearance

How long does the result last?

The results are immediate after the first treatment. In general, the results can last from 6 to 9 months. Sometimes the results last up to a year, depending on individual factors such as skin type, age, lifestyle and technique used by the doctor.

Frequently asked questions

How does a treatment work?

Treatments with Croma HA Fillers are non-surgical procedures with minimal recovery time. They produce immediate and natural-looking results. Depending on your skin and your individual wishes and needs, the doctor will choose the most suitable product from the Croma HA Filler portfolio. Due to the similarity of the hyaluronic acid used in Croma HA fillers to the body's own substance, a prior allergy test is not necessary. The treatment is quick and uncomplicated. The injection itself takes only 15-30 minutes on average. After the treatment you can go about your normal everyday life.

Is the treatment painful?

Most people find filler injections relatively painless. The addition of lidocaine, a mild anesthetic, to certain products makes the injection even more comfortable for you. In addition, Croma HA fillers are inserted into the skin with thin-walled needles specifically designed for optimal patient comfort. Depending on your sensitivity and the particular treatment area, a local anesthetic can be applied beforehand if needed.

How long does the effect last?

The results of an aesthetic treatment with Croma HA fillers are long-lasting, but not permanent; depending on the product used, the area injected and your individual predisposition, the results can last from several months to a year.

For whom may the treatment not be performed? Are there any exclusion criteria?

Treatments with Croma HA fillers should not be used on:

- Individuals who are prone to hypertrophic scars or keloid formation

- Persons who unfortunately suffer from an autoimmune disease or receive immunotherapy

- Persons with hypersensitivity to hyaluronic acid, lidocaine hydrocloride or amide-type local anesthetics

- pregnant or breastfeeding women

- Persons under 18 years of age

- Persons with infections or inflammations in the regions to be treated (acne, herpes,...)

- Persons receiving antiplatelet drugs (e.g. ASA) should not be treated without consulting their doctor

- Persons who have already undergone treatment with permanent fillers at the site

- Persons with cutaneous, inflammatory and/or infectious processes in the treatment area (e.g. acne, herpes...)

- People who have undergone laser therapy, chemical peeling, dermabrasion, or mesotherapy

Are there any special recommendations?

- Before treatment

Before treatment, talk to your doctor about your wishes, needs and expectations. Inform your doctor about your medical history and previous aesthetic treatments with other products. To reduce the risk of bruising and bleeding at the injection site, anticoagulants (such as Aspirin™, Marcoumar™, etc.) and anti-inflammatories should not be taken for one week prior to treatment with Croma HA Fillers.

- After treatment

For best treatment results, protect your skin the day after treatment and do not touch the treated areas. You should not wear makeup for at least 12 hours afterwards and avoid sunbathing, high temperatures, saunas and steam baths for the first week after treatment. If you feel discomfort after the treatment, you can place an ice pack on the injection site for a short time to reduce swelling.

What are the possible side effects?

Croma is a leading expert in hyaluronic acid fillers and applies the highest safety standards to ensure the quality and safety of the products. Nevertheless, after treatment with Croma HA fillers - despite impeccable quality - discomfort or side effects may occur immediately after the injection or in the first days.

Slight redness and swelling may occur at the injection sites, which usually disappear by themselves after a few hours. Apart from slight bleeding due to the injection, mild edema or erythema may develop, which may be itchy or painful if pressure is applied. In rare cases, small hematomas, indurations, and nodules may form in the treated areas and resolve within a few days. These reactions may last for a week. Please inform your doctor if inflammatory reactions or other adverse reactions last longer than one week so that they can be treated appropriately.

"The following side effects and reactions have been observed with similar products: Abscess, angioedema, bacterial infection, beading/clumping, bleeding, bruising, burning, discoloration (dispigmentation), malaise, edema, erythema, visibility of injection sites, mass formation, firmness, Granulomas , hematoma, herpes reactivation, hypersensitivity, swelling at implant site, implant visibility, induration, inflammation, irritation, itching, livedoid drawing, after accidental arterial embolization, Malar edema, migration, necrosis due to vasoconstriction, nodules (inflammatory and non-inflammatory), numbness, pain, paresthesia, redness, retinal artery occlusion, cicatricial sarcoidosis, scleromyxedema (generalized), swelling, telangiectasia, tenderness, vasculitis, vasospasm, vasovagal reaction during injection, visual loss due to retinal artery occlusion (in very rare cases).

What is hyaluronic acid?

Hyaluronic acid (HA) is a natural element of our body (skin, joints and eyes). From a chemical point of view, hyaluronic acid is a long chain, made of repeating sugar molecules.Due to the chemical structure, HA has a very high water-binding capacity and promotes, for example, the preservation of moisture, firmness and elasticity of the skin.

What influence does hyaluronic acid have on skin aging?

As we age, the level of hyaluronic acid decreases and the condition of our skin deteriorates. Environmental factors such as excessive sun exposure, smoking, poor diet, stress and the natural aging process affect the degradation of hyaluronic acid levels in the body

Our skin becomes thinner, drier and loses elasticity. Wrinkles appear and the overall harmony of the face changes. The cheeks, lips, eyebrows, temples and jaw are most affected. Find out how you can reverse the signs of aging without surgery and without pain and choose Croma HA Filler

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