PRP hair growth tubes: how the therapy works

PRP tubes for hair growth - effective therapy against hair loss

The treatment of hair loss with PRP (platelet-rich plasma) has established itself as an effective and safe method. With the introduction of PRP tubes for hair growth, which are additionally enriched with melatonin, the therapy has been further optimized. These tubes offer doctors and patients an innovative way of prolonging the hair growth phase and effectively reducing hair loss. In this article, you will learn how PRP stimulates hair growth, why melatonin PRP tubes are particularly effective and how the treatment is carried out step by step - including important information on the addition of an anticoagulant such as heparin.

How does PRP stimulate hair growth?

PRP (platelet-rich plasma) is an autologous substance obtained from the patient's blood. It contains a high concentration of platelets and growth factors that promote tissue regeneration.

platelet-rich plasma

Mechanisms of action of PRP:

  1. Promotion of hair follicle stem cells: PRP stimulates hair follicle stem cells (e.g. Lgr5 cells) and promotes their proliferation.
  2. Improved blood circulation: PRP stimulates angiogenesis so that hair follicles are supplied with more oxygen and nutrients.
  3. Prolongation of the anagen phase: The active growth phase of the hair cycle is prolonged, resulting in thicker and stronger hair.
  4. Anti-inflammatory effect: PRP reduces micro-inflammation in the scalp, which can damage hair follicles.
  5. Inhibition of cell degradation: PRP protects hair follicles from apoptosis (cell death) by inhibiting inflammatory signaling pathways such as JAK-STAT.

Results from studies show that PRP significantly improves hair density and reduces hair loss - especially in androgenetic alopecia.

Why is melatonin a game changer for hair treatment?

Melatonin, known as the "sleep hormone", not only has a central function in the circadian rhythm, but also in the scalp and hair follicles. It binds to melatonin-specific receptors that are expressed in the hair follicle, where it regulates important processes for hair growth.

Why are PRP tubes with melatonin particularly effective?

The combination of PRP with melatonin offers an additional, scientifically proven benefit for hair treatment. Melatonin, known as a powerful antioxidant, has also proven itself in hair medicine. It protects hair follicles from oxidative stress and promotes the hair cycle.

Benefits of melatonin PRP tubes:

  1. Oxidative protection: melatonin neutralizes free radicals and protects hair follicles from damaging influences.
  2. Stimulation of the hair cycle: Melatonin modulates the hair cycle and supports a longer anagen phase.
  3. Reduction of DHT: Melatonin helps to reduce the effect of dihydrotestosterone (DHT), a major cause of hair loss.
  4. Synergy with PRP: The combination of melatonin and PRP increases the regeneration and growth of hair follicles.

Important note: The PRP tubes with melatonin require the addition of an anticoagulant such as heparin to prevent the blood from clotting and to ensure the quality of the PRP.

PRP tubes with melatonin

Treatment plan for melatonin PRP tubes

Treatment with Melatonin PRP tubes is carried out in several stages in order to optimally promote hair growth. According to the treatment plan, about four sessions are necessary for visible results.

Number of treatments and intervals:

  • Number of treatments: 4 sessions with 2 Melatonin PRP tubes per treatment.
  • Treatment interval: Every 2-3 weeks.
  • First visible results: After 3 months.

Step-by-step instructions: Hair treatment with melatonin PRP tubes

1. Preparation

  • The patient comes with freshly washed hair (without hairspray, hair conditioner or other products).
  • The melatonin tubes are mixed with 18 units of heparin (e.g. Heparin Sodium 500 I.U./10 x 5 ml) before the blood sample is taken. This is best done with an insulin syringe.

2. Blood collection and PRP collection

  • 10-30 ml of blood is taken and filled into the prepared melatonin PRP tubes.
  • The tubes are processed in a centrifuge to separate the PRP from the remaining blood.

3. Injections

  • Needle used: Kipic needle 27 G - 4 mm.
  • Injection technique: The PRP is injected in boluses of 0.2 ml into the deep dermis and the transition to the subcutis.
  • Two Melatonin PRP tubes are used per session.

4. PRP in combination with microneedling

  • After the injections, an additional PRP tube is used for microneedling therapy.
  • Microneedling stimulates blood circulation and enhances the effect of the PRP. The plasma is worked well into the scalp.

5. Home application

  • Another PRP tube is prepared for use as a hair treatment:
    • The plasma is filled into a syringe, sealed with a stopper, labeled and frozen.
    • One week after the treatment, the thawed plasma is applied to the freshly washed scalp in the evening and massaged in. It can be washed out the next morning.

6. Aftercare

  • After the treatment, the patient should wash their hair the following day.
  • Sport, sauna and intensive sun exposure are not recommended for the next few days.

7. Optional supplement: mesotherapy

  • Between PRP treatments, a hair cocktail with B vitamins (e.g. panthenol, biotin) can be used to additionally activate hair growth.

Why is this treatment approach so effective?

The combination of PRP therapy, melatonin PRP tubes, microneedling and home treatments leads to comprehensive stimulation of the hair follicles. The addition of heparin ensures the quality of the PRP, while microneedling and home treatments further enhance the effect.

Advantages:

  • Holistic treatment: The combination of different methods maximizes the results.
  • Personalized therapy: The plan can be individually adapted to the patient's needs.
  • Scientifically sound: The therapy is based on the latest findings in hair medicine.

Possible risks and side effects of PRP therapy

1. Local reactions at the injection site

  • Pain or discomfort: Mild pain may occur during the injections. This is usually temporary and can be minimized by using thin needles (e.g. Kipic 27 G).
  • Redness and swelling: After the treatment, redness or slight swelling may occur at the injection sites. This usually subsides on its own within a few hours to days.
  • Hematomas (bruising): Occasionally, small bruises may occur, especially in patients with sensitive skin or when injecting into areas with a particularly high blood supply.

2. Infections

  • As the treatment requires injections, there is a small risk of infection at the injection sites. This risk can be minimized by strict hygiene precautions and the use of sterile materials.

3. Allergic reactions

  • As PRP is obtained from the patient's own blood, allergic reactions are extremely rare. However, the addition of anticoagulants such as heparin or the use of melatonin topicals can lead to hypersensitivity reactions. Patients should be checked in advance for possible allergies.

4. Scalp sensitivity

  • After treatment, some patients report increased sensitivity of the scalp. This is usually temporary and disappears within a few days.

5. Temporary hair loss

  • In rare cases, a shedding effect may occur after PRP treatment. This is a temporary hair loss caused by the activation of the hair follicles. This effect is usually a sign that the hair follicles are entering the growth phase (anagen phase).

6. Side effects of melatonin

  • Hypersensitivity: Although rare, some patients may be sensitive to melatonin. This could manifest itself in the form of itching or mild skin irritation.
  • Systemic effects: As melatonin is applied topically in low doses, systemic side effects such as fatigue are extremely unlikely. Nevertheless, the patient should be informed about possible effects.

7. Risks due to improper use

  • Incorrect centrifugation or inadequate addition of heparin could impair the quality of the PRP. This can lead to reduced efficacy or even adverse reactions.
  • Improper injection techniques, such as injections that are too deep or superficial, can cause pain, swelling or uneven distribution of the PRP.

Contraindications for PRP therapy

PRP therapy is not suitable for all patients. There are certain medical conditions for which the treatment is not recommended:

  1. Blood clotting disorders: Patients with thrombocytopenia, hemophilia or other clotting disorders are not suitable for PRP therapy.
  2. Autoimmune diseases: Diseases such as lupus or rheumatoid arthritis may increase the risk of side effects.
  3. Active infections: Treatment should be postponed in the case of infections of the scalp or systemic infections.
  4. Pregnancy and breastfeeding: Although no specific risks are known, PRP therapy is not recommended during pregnancy and breastfeeding for precautionary reasons.
  5. Cancer: Patients with active tumors or a history of cancer should refrain from PRP therapy.

How can risks be minimized?

  • Experienced doctors: PRP therapy should only be carried out by qualified doctors or alternative practitioners who are familiar with the technique.
  • Hygiene: Strict hygiene standards are crucial to avoid infections.
  • Patient education: Patients should be fully informed about possible risks and side effects before treatment.
  • Individual adaptation: The therapy should be individually adapted to the patient, especially with regard to the dosage of melatonin and the addition of heparin.
  • Aftercare: Patients should carefully follow the aftercare instructions, such as avoiding sport, sauna or intensive sun exposure in the first few days after treatment.

Conclusion: opportunities and risks of melatonin PRP therapy

PRP therapy with melatonin PRP tubes is a state-of-the-art, effective and relatively safe method of treating hair loss. It offers numerous benefits, including prolonging the growth phase, strengthening the hair follicles and reducing inflammation. However, the potential risks and side effects should not be underestimated. Careful patient selection, correct application and strict adherence to aftercare can help to make the therapy as safe and successful as possible.

For patients looking for a natural and minimally invasive solution to hair loss, PRP therapy is a promising option - provided it is carried out by experienced professionals.

Studies

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