Profhilo - Bio Remodeling
Profhilo - Bio Remodeling

PROFHILO H+L Bio Remodeling | Anti-aging redefined

PROFHILO® H+L by IBSA is an injectable hyaluronic acid product for professional use. Its formulation combines high- and low-molecular-weight hyaluronic acid in stabilised hybrid complexes and contains a total of 64 mg of hyaluronic acid in 2 ml.

PROFHILO® H+L is used for bio-remodelling and differs in its concept and product characteristics from conventional volumising hyaluronic acid fillers.

Pack contents:
1 × 2 ml pre-filled syringe
2 × 29G × 1/2" needles

100405
immediately available
€116.00

€63,500.83 per Liter

incl. tax, plus shipping Shipping excluded | Delivery time 2 - 3 days within Germany* | Abroad may vary

Graduated price - order from quantity Unit price You save in total
3 €115.00 €3.00
5 €114.50 €7.50
 
IBSA Derma · Medical device

PROFHILO® H+L – hyaluronic acid for professional bio-remodelling

PROFHILO® H+L combines high- and low-molecular-weight hyaluronic acid at a concentration of 64 mg per 2 ml. The stabilised Hybrid Cooperative Complexes are created using the patented NAHYCO® Hybrid Technology – without BDDE as a chemical cross-linking agent.

The product is intended for professional aesthetic-medical use. Its concept focuses on bio-remodelling of tissue and skin quality rather than the classic, localised volume augmentation of a dermal filler.

64 mg / 2 mltotal hyaluronic acid
H-HA + L-HAtwo molecular weights
1 × 2 mlprefilled syringe
2 × 29Gneedles, 13 mm
PROFHILO H+L pack with 2 ml prefilled syringe
Product concept

What is PROFHILO® H+L?

PROFHILO® H+L is a sterile hyaluronic-acid medical device from IBSA. The formulation contains 32 mg high-molecular-weight and 32 mg low-molecular-weight hyaluronic acid in a 2 ml prefilled syringe.

Unlike classic chemically cross-linked hyaluronic-acid fillers, stabilisation is achieved by a patented thermal manufacturing process. The two hyaluronic-acid fractions are combined into stabilised Hybrid Cooperative Complexes. BDDE is not used for this process.

Important classification: PROFHILO® H+L is designed as a bio-remodelling product. It should therefore not simply be described as a classic “hyaluronic-acid filler” whose primary purpose is targeted volume projection or contouring.
NAHYCO® Hybrid Technology

Thermally stabilised – without BDDE

NAHYCO® Hybrid Technology combines high- and low-molecular-weight hyaluronic acid through a controlled thermal process.

H-HAhigh-molecular-weight hyaluronic acid
L-HAlow-molecular-weight hyaluronic acid
64 mgtotal concentration per 2 ml
BDDE-freeno chemical BDDE cross-linking
Treatment areas

Which areas is PROFHILO® intended for?

IBSA Germany lists the face, neck, décolleté and hands among the indications for PROFHILO® H+L. Suitability in an individual case depends on the current instructions for use, the clinical assessment and the professional decision of the qualified practitioner.

Faceprofessional aesthetic-medical use
Neckwith a product-specific application concept
Décolletéaccording to current manufacturer information
Handssee IFU for the complete list of indications
PROFHILO H+L product pack
Original guides

BAP technique: guides for face and neck

PROFHILO® is often associated with the BAP technique – Bio Aesthetic Points. The original documents from the previous product description remain directly accessible here and show the product-specific point scheme for the face and neck.

These documents do not replace the current instructions for use or professional training. Anatomy, patient selection, injection depth and the specific procedure remain the responsibility of qualified healthcare professionals.

PROFHILO Winner 2016 – Aesthetics Awards Product Innovation of the Year
Awards

An internationally recognised product line

The Aesthetics Award 2016 graphic used in the previous product description is retained. It identifies PROFHILO® as the winner of the Barry Knapp Award for Product Innovation of the Year.

The PROFHILO® product line has also received later recognition: IBSA reports an “Injectable Product of the Year” award at the 2022 Aesthetics Awards.

Pack contents

PROFHILO® H+L at a glance

ProductPROFHILO® H+L
Manufacturer / brandIBSA
Presentation1 × 2 ml
Hyaluronic acid64 mg / 2 ml
HA composition32 mg H-HA + 32 mg L-HA
Included needles2 × 29G × 13 mm
TechnologyNAHYCO® Hybrid Technology
Chemical cross-linkingwithout BDDE
For professional users

Medical device for professional use

PROFHILO® H+L is a medical device under Regulation (EU) 2017/745 (MDR). Application, patient selection and treatment planning must be carried out by appropriately qualified professionals.

The current manufacturer instructions for use are authoritative for indications, contraindications, warnings, adverse effects, application technique and traceability.

Sale exclusively to professional users and their purchasers

Applicable legal requirements for the purchase, storage, documentation and use of medical devices must be observed.

FAQ for professionals

Frequently asked questions about PROFHILO® H+L

How much hyaluronic acid does PROFHILO® H+L contain?

One 2 ml prefilled syringe contains a total of 64 mg hyaluronic acid: 32 mg high-molecular-weight (H-HA) and 32 mg low-molecular-weight hyaluronic acid (L-HA).

Is PROFHILO® H+L chemically cross-linked with BDDE?

No. IBSA describes PROFHILO® as thermally stabilised hyaluronic acid based on NAHYCO® Hybrid Technology. The manufacturing process does not use BDDE as a chemical cross-linking reagent.

Is PROFHILO® a classic dermal filler?

IBSA positions PROFHILO® H+L as a bio-remodelling product. Its objective therefore differs from classic fillers, where targeted volume augmentation or contour projection is typically the main focus.

Which needles are included?

According to current IBSA Germany information, the pack contains one 2 ml prefilled syringe and two 29G × 13 mm needles.

Where can I find the BAP guides?

The PDF guides for face and neck are linked directly above. The current manufacturer instructions for use remain authoritative for application.

More PROFHILO® products

PROFHILO® in the professional range

Other PROFHILO® products are available for different treatment areas and product-specific intended uses. Product selection and application must follow the respective instructions for use and professional assessment.

Product information based on current manufacturer information from IBSA Germany / IBSA Derma. The current instructions for use and valid intended purpose of the medical device are authoritative. Responsible economic operator according to the manufacturer: IBSA Pharma GmbH, Königsallee 14, 40212 Düsseldorf, Germany. Open manufacturer information.
Features

GPSR – General Product Safety Regulation

Responsible Economic Operator according to GPSR:

IBSA Institut Biochimique SARegistered Office

Via Pian Scairolo 49

CH-6912 Lugano-Pazzallo

 

Management and Offices

Via del Piano 29

CH-6926 Collina d’Oro-Montagnola+41 58 360 10 00

https://www.ibsagroup.com/contact.html

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