Rejuran Healer – Polynucleotide Skin Booster 2 × 2 ml
Rejuran Healer is an injectable skin booster based on highly pure polynucleotides (PN) to support skin quality as part of aesthetic treatment protocols.
– For the face, neck, and décolleté
– For use on structurally damaged, dry-looking, or mature skin
– Focuses on biostimulation rather than volume effect
– For injection by appropriately qualified medical professionals only
Medical device; use in accordance with the manufacturer's instructions for use (IFU). Package: 2 pre-filled syringes, 2 ml each.
PN skinbooster for medical professionals
Polynucleotides in a prefilled syringe: for protocols focused on skin quality rather than volume
Rejuran Healer is an injectable PN-based medical device for professional use. According to the European manufacturer and distribution information available, the product family is listed as a Class III medical device with CE 2265. The labelling and current IFU of the version actually supplied remain controlling.
- Instead of a volumising filler when skin quality, not contour, is the main objectivePN gel, not primarily designed for conventional volume enhancement
- Instead of preparation in the practiceready to use in 2 prefilled syringes of 2 ml each, without blood collection or centrifugation
- Instead of a cosmetic or microneedling serumClass III medical device with CE marking, for injection by qualified professionals
Approx. 137,50 € per prefilled syringe incl. VATManufacturer: PharmaResearch Co., Ltd., Republic of Korea. For qualified medical professionals only.
What are polynucleotides?
Polynucleotides, abbreviated PN, are longer-chain DNA fragments. According to the manufacturer, the PN used for Rejuran are derived from salmon DNA and processed using the company’s proprietary DOT™ technology (DNA Optimizing Technology). The result is an injectable PN gel.
- Source material
- Salmon DNA, according to the manufacturer
- Processing
- DOT™ technology
- Product form
- injectable PN gel
- Pack
- 2 prefilled syringes of 2 ml each
Schematic illustration, not to scale; fragment lengths and processing steps are not shown. More background on the brand and Rejuran variants is available in the “About REJURAN” tab.
Positioning alongside hyaluronic acid fillers and PRP
Rejuran Healer is intended for practices that treat PN-based injection protocols as a separate category alongside hyaluronic acid fillers, PRP or device-based procedures. The three categories differ mainly in source material, preparation and regulatory classification.
| Feature | |||
|---|---|---|---|
| Source material | processed DNA fragments (polynucleotides) | hyaluronic acid, usually cross-linked | patient’s own blood |
| Preparation | ready-to-use prefilled syringe | ready-to-use prefilled syringe | prepared in the practice: blood collection and centrifugation |
| Regulatory classification | medical device; Class III according to the available EU documentation | medical device; risk class depends on the specific product | autologous blood preparation; medicinal-product and transfusion-law requirements may apply |
| Main focus | not conventional volume enhancement | volume and contour (volumising filler) | depends on preparation and protocol |
General classification of the product categories; no assessment of efficacy and no ranking. More detail in the professional article on polynucleotide skinboosters.
For the face, neck and décolletage
The available product and manufacturer information lists these three areas. Choice of area, technique, injection depth, product amount and treatment interval is a medical decision based on the individual situation, indication and current manufacturer information.
- Face: for professional use in accordance with the intended purpose and current IFU.
- Neck: assess suitability and technique for the individual patient; take anatomical features and risk zones into account.
- Décolletage: use following professional assessment and within a documented treatment plan.
Before every use
Practice checklist
0 of 4 checkedAll four items checked.
Checklist aid only; no entries are stored. This product description does not replace the manufacturer’s IFU or appropriate medical training.
Regulatory classification
- Product type
- Class III medical device
- CE marking
- CE 2265
- Manufacturer
- PharmaResearch Co., Ltd., Republic of Korea
- Intended users
- medical professionals authorised under national law
Information according to European manufacturer and distribution documentation. For purchasing, supply and use, the labelling, conformity information and current IFU of the version supplied remain controlling. The product must not be used like a topical serum or a microneedling ampoule.
Frequently asked questions
Is Rejuran Healer a dermal filler?
Rejuran Healer is an injectable PN product whose main focus is not conventional volume enhancement. It should therefore not be classified, either professionally or during consultation, like a traditional hyaluronic acid volumising filler.
What does PN stand for?
PN stands for polynucleotides. These are longer-chain DNA fragments used in Rejuran as processed material for medical-aesthetic injection protocols.
How does Rejuran Healer differ from PRP?
Rejuran Healer is an industrially manufactured medical device supplied in a prefilled syringe. PRP is prepared in the practice from the patient’s own blood. In Germany, medicinal-product and transfusion-law requirements may be relevant depending on preparation and use. The two are not generally interchangeable; selection is a medical decision.
Who may administer Rejuran Healer?
Only appropriately qualified medical professionals or professionals authorised under national law. The specific authorisation depends on the country and applicable professional law.
For which areas is the product intended?
The available product and manufacturer information lists the face, neck and décolletage. The intended purpose stated in the current IFU of the supplied product version remains decisive.
Can Rejuran be combined with PRP, fillers or device-based procedures?
A combination must not be assumed to be suitable in general. The practitioner determines sequence, interval, product compatibility and patient suitability based on the relevant IFU and the individual situation.
Is Rejuran Healer suitable for microneedling or topical use?
No. Rejuran Healer is an injectable medical device, not a cosmetic microneedling serum. It is not intended for topical or cosmetic use.
Where can I find contraindications and complete safety information?
Binding information is provided in the current manufacturer IFU for the supplied product version. It must be read in full before first use and remain available in the practice.
For professionals: Rejuran Healer is intended exclusively for use by medical professionals who are appropriately qualified or authorised under national law. The current IFU and the labelling of the batch supplied always take precedence.
REJURAN® – Polynucleotide products by PharmaResearch
REJURAN® is a product line from the South Korean manufacturer PharmaResearch. The professional injectable products are based on polynucleotides (PN) from DNA-based source material. The international Rejuran portfolio includes several variants for different product-specific applications. This brand overview classifies the Rejuran products and distinguishes the injectable line from the separate REJURAN® Cosmetics range.
What is Rejuran?
Rejuran is a PharmaResearch brand for PN-based products used in medical aesthetics. The classic injectable line is based on polynucleotides. PharmaResearch describes its proprietary DNA Optimizing Technology, or DOT™, in connection with these DNA-based materials.
Rejuran should not be equated generally with a cosmetic serum or a conventional hyaluronic acid volumising filler. The composition, intended purpose, storage and use of each specific product are determined by its labelling and current manufacturer information.
Which Rejuran products are available?
PharmaResearch markets several products internationally under the REJURAN® brand. The variants differ, among other things, in formulation and product-specific positioning.
The classic PN variant
The core variant of the injectable Rejuran line is based on polynucleotides (PN). It forms the basis of the internationally established REJURAN® product family.
Specialised product variant
REJURAN® i also belongs to the PN-based product family and is marketed by the manufacturer as a distinct variant within the international portfolio.
Distinct PN formulation
REJURAN® S is another specialised variant within the product family. The documentation for the respective market version is always decisive for its specific classification.
PN with additional components
REJURAN® HB plus differs from the pure PN variants through a combined formulation that additionally contains sodium hyaluronate and lidocaine hydrochloride.
The international manufacturer portfolio does not automatically reflect availability or regulatory status in a particular country. The labelling, instructions for use and manufacturer documentation of the specific product version are always decisive.
Distinguishing Rejuran injectable products from Rejuran Cosmetics
REJURAN® injectable products
The professional core line includes injectable PN-based products and product-specific combinations. They are intended for appropriately qualified users and must be assessed according to the current product labelling and manufacturer IFU.
REJURAN® Cosmetics
PharmaResearch also markets topical skincare products under REJURAN® Cosmetics. According to the manufacturer, this cosmetics line uses ingredients including c-PDRN® and should not be confused with the injectable PN products.
PN and PDRN: related terms, but not generally interchangeable
PN and PDRN refer to DNA-based materials, but the terminology is not always used consistently in product communication and scientific literature. PharmaResearch identifies the material in the classic injectable REJURAN® line as PN – Polynucleotide; REJURAN® Cosmetics uses, among other ingredients, c-PDRN®.
A detailed professional overview of polynucleotides, Rejuran, hyaluronic acid and PRP is available in the prpmed article on polynucleotide skin boosters.
What does DOT™ mean?
DOT™ stands for DNA Optimizing Technology. PharmaResearch uses this term for its proprietary technology for processing DNA-based source materials within its PN and PDRN product areas.
PharmaResearch and Rejuran
The manufacturer behind REJURAN® is PharmaResearch Co., Ltd. from the Republic of Korea. The company operates in several areas, including pharmaceuticals, medical devices and dermocosmetics, and uses DNA-based materials such as PN and PDRN across different product lines.
More about Rejuran, polynucleotides and professional classification
This brand page intentionally provides an overview only. Differences between polynucleotides, hyaluronic acid fillers and PRP, as well as the current evidence base, are discussed separately in the professional article.
Rejuran Healer at prpmed
prpmed offers Rejuran Healer 2 × 2 ml for appropriately qualified medical professionals. Product data, availability and ordering information are provided exclusively on the product page.
Frequently asked questions about the Rejuran brand
What is Rejuran?
Rejuran is a PharmaResearch brand. The classic professional injectable line is based on polynucleotides (PN) and includes several product-specific variants.
Who manufactures Rejuran?
The REJURAN® product line is manufactured by PharmaResearch Co., Ltd. in the Republic of Korea.
Which Rejuran products are available?
The international portfolio includes REJURAN®, REJURAN® i, REJURAN® S and REJURAN® HB plus, among others. Composition, intended purpose and availability vary by product version and market.
Is Rejuran PN or PDRN?
PharmaResearch identifies the material in the classic injectable REJURAN® line as PN – Polynucleotide. The manufacturer also uses PDRN or c-PDRN® in other product areas, so the terms should not be treated as universally interchangeable.
Is Rejuran Cosmetics the same as the injectable Rejuran line?
No. REJURAN® Cosmetics is a separate dermocosmetic skincare range with topical products and should not be confused with the professional injectable REJURAN® products.
Can I buy Rejuran at prpmed?
prpmed offers Rejuran Healer 2 × 2 ml for appropriately qualified medical professionals. Price, pack contents and availability are listed on the product page.
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