Platelet-rich plasma therapy (PRP) in the treatment of melasma
Melasma - the cause of facial spots
Melasma is a chronic dermatological condition that is easy to recognise and requires no special diagnosis; it is often detected by the dermatologist during a simple clinical examination.
Hyperpigmentation is one of the largest and most common problems of the skin, especially skin prone to tanning. Although it can occur in both sexes, melasma affects women in 90% of cases because they are genetically more predisposed.
The presence of melasma can be detected with the naked eye because it is the appearance of pigmented patches, areas of tissue that are darker in colour than the normal skin tone surrounding them.
The small areas where pigment proliferation can be seen have a colour that varies from brown to grey-brown and are mainly found on the face.
Melasma is therefore quite common on the cheeks, nose, forehead, chin, the skin above the upper lip and around the mouth, but can also occur on other parts of the body that are frequently exposed to the sun, such as the neck, chest and arms.
Generally not dangerous, this skin condition is caused by an excess of melanin in the skin, the brown pigment that normally gives the skin its colour, and in this case it is deposited in very specific areas.
Although harmless, melasma can have a dramatic effect on a person's appearance, especially because it is on the face and because it is a common blemish that is very difficult to remove over time.
Was ist PRP (Platelet Rich Plasma)?
Platelet rich plasma (PRP) is an effective cellular biological treatment in the field of orthopaedic medicine, musculoskeletal medicine, sports injury medicine and of course very often in cosmetic aesthetics, especially in the treatment of hair loss and skin rejuvenation.
The reason PRP therapy is so popular in the treatment of hair loss and skin rejuvenation is because of its ability to stimulate hair follicles and promote and restore new skin collagen.
In musculoskeletal medicine, PRP treatment is used to treat a variety of distortions/tears, ligament/damage to joints, delayed lesions, arthritis/board degeneration and joint retention. PRP therapy is used to facilitate the repair and healing of damaged tissue.
PRP treatment is a very common and simple form of regenerative medicine that consists of a special procedure in which specialised bioactive growth factors are extracted from the patient's own blood, then concentrated and introduced into an area of tissue damage to stimulate the healing process, reduce inflammation and decrease pain.
Our blood is made up of red blood cells, white blood cells, plasma and platelets. It is the platelets that release healing proteins called growth factors, and it is these growth factors that speed up tissue healing. By increasing these platelets, we are able to deliver an enhanced mix of growth factors that can dramatically improve tissue repair and healing.
How does platelet-rich plasma therapy (PRP therapy) work?
During the PRP procedure, blood is taken from the patient with PRP tubes and centrifuged with a special PRP centrifuge to separate the cells from the platelets and serum. Plasma is then injected into the desired areas.
Pilot study on PRP treatment of melasma
In a randomised, placebo-controlled study on the treatment of melasma with PRP, a Thai research team investigated the efficacy of PRP therapy in a group of melasma patients. A cohort of 10 women (mean age 46.2 years) with bilateral mixed-type melasma were enrolled in the single-blinded, prospective study.
The researchers injected platelet-rich plasma intradermally into one side of the face every fortnight for a total of four treatment sessions, while simultaneously injecting saline into the other (control) side. Outcomes were measured using the modified Melasma Area and Severity Index (mMASI), Mexameter and Antera 3D.
Participant satisfaction was assessed at baseline and after 2, 4, 6 and 10 weeks.
The results of the pilot study, published in the Journal of Cosmetic Dermatology, showed that platelet-rich plasma injections were associated with an improvement in melasma condition within 6 weeks of treatment. Both the mMASI score and melanin levels measured with Antera 3D showed significant improvement on the side of the face treated with PRP injections compared to the control side between measurements at baseline and those at week 6. The Antera 3D measurement also showed a reduction in mean wrinkle level from measurements at baseline to week 4. In addition, reported patient satisfaction increased significantly over the duration of PRP treatment.
The study authors reported that there was no difference between the PRP and control sides of the face in terms of erythema or melanin indices measured with the Mexameter - although there was a trend towards less pigmentation in the latter. All side effects that occurred during treatment were of low severity and resolved spontaneously.
The authors of the study acknowledge the limitations of their study, including: the small size of the cohort, the participation of women only, and the short follow-up period of only one month after treatment.
The latest study showed not only a significant improvement in melasma symptoms and patient satisfaction associated with regular injections of platelet-rich plasma, but also the added benefit of wrinkle reduction from week 4 onwards. This was "likely due to the rejuvenating effect of PRP, which has been demonstrated in many studies, stimulating fibroblast and collagen proliferation and increasing hyaluronic acid synthesis", according to the study authors.
How do I prevent a relapse of melasma after successful PRP therapy?
After your melasma has cleared, you may need to continue treating your skin. Your dermatologist may call this maintenance therapy. Maintenance therapy can prevent the melasma from coming back.
You can prevent your melasma from returning by wearing sunscreen and a wide-brimmed hat every day.
Avoid sun exposure without sunscreen. Reduce screen time in front of your LED TV, tablet, mobile phone and computer.
Always listen to your doctor's advice and follow your treatment plan carefully.
PRP treatments in veterinary medicine: a promising prospect for the future
Platelet rich plasma (PRP) treatments are a promising future prospect in veterinary medicine. Platelet therapy has been established in both veterinary and human medicine for the treatment of poorly perfused tissues.Read more
Autologous blood therapy for hair
Autologous blood therapy is an innovative and safe treatment method that is becoming increasingly popular for hair loss and thinning hair.Read more
Can PRP be combined with biorevitalization?
Are PRP and biorevitalization compatible with each other? The preparations act on different processes in the body and complement each other perfectly.Read more
PRP injections for lips
A PRP treatment for lips consists of a painless injection of platelet-enriched plasma into the skin. The resource for the procedure is the patient's blood, from which platelets are obtained in a concentrated form. These are responsible for stimulating cellular functions and inhibiting the aging process.Read more
Questions and answers about carboxytherapy
The main cause of aging of the epidermis is a lack of oxygen in the tissues.Read more
Answers to frequently asked questions about PRP treatment
What is PRP treatment? It is a medical technology that uses an injectable form of autoplasm derived from blood platelets.Read more
PRP therapy: its therapeutic properties
PRP therapy is an injectable procedure in which a patient's platelet-rich plasma is injected into a body part that requires rapid healing, i.e., it is intended to accelerate regeneration and stimulate the growth of the body's own cells.Read more
Saving Lives: Blood Plasma
Blood plasma is a versatile drug with pronounced detoxifying and hemostatic properties. It has various functions (nutrition, transport, buffering and others).Read more
PRP nebulizer for lung diseases - an innovative treatment method
One of the most serious effects of coronavirus disease (COVID19) is lung diseases such as acute respiratory distress syndrome. In the absence of effective treatments, it is necessary to search for new therapies and therapeutic targets. Platelets play a fundamental role in respiratory diseases derived from viral infections, as they are the first line of defense against viruses and are essential for maintaining lung function.Read more
What is regenerative medicine?
Regenerative medicine encompasses many different innovative therapies whose goal is autologous (the body's own) tissue regeneration.Read more
PRP treatment in sports medicine
PRP is an agent used to biologically stimulate tissue healing. It can be an effective method of treating sports injuries and is therefore becoming increasingly popular. PRP procedure can and should play an important role in solving the most current orthopedic problems in the present and in the future!Read more
PRP treatment for rosacea
PPR allows the skin to rejuvenate and repair itself, which can help relieve and calm the symptoms of rosacea.Read more
Treatment of cellulite with PRP (platelet rich plasma)
In the modern world, 90% of women struggle with body blemishes (cellulite, stretch marks). The introduction of autologous platelet plasma can reduce the severity of these defects and improve the quality and appearance of the skin.Read more
Hair Loss Support and Treatment
Hair loss, also called alopecia, is complete or partial baldness due to hormonal changes or physical or psychological stress.Read more
FUE hair transplantation
FUE transplants are the most common and successful method of curing hair loss. Find out more about the FUE hair transplant process.Read more
You want to make plasma gel? What equipment do you need to do this?
We are often asked what equipment is needed for plasma gel? You will find an answer in this article.Read more
Plasma growth factors in cerebral palsy
The use of plasma growth factors has opened up a new clinical field of application in medicine and given rise to a new discipline called regenerative medicine. In many areas such as traumatology, dental implants or anaesthesia, the use of this biotechnology can improve patients' quality of life.Read more
PRP therapy for tendonitis
Repetitive movements can stretch tendons and cause pain, swelling and limited movement. Try PRP therapy to perform tendon repair, which can heal hard tissue and not just mask pain and cause long-term damage like traditional treatments.Read more
Learn more about PRP treatment: how it works and what it does.
PRP treatments are an innovative technique that helps improve skin quality and treat certain skin conditions. These treatments are safe, gentle and effective and can help improve the appearance and condition of the skin. Learn more about PRP treatments, how they work, and what results you can expect.Read more
Can carpal tunnel syndrome be treated with PRP therapy?
Carpal tunnel syndrome (CTS) is a condition that affects a patient's quality of life. About three to six percent of the adult population in the United States suffers from carpal tunnel. Some cases of CTS improve on their own, but many require medical intervention. Unfortunately, many modern medical treatments offer only short-term relief for patients. They do not solve the underlying problem that causes CTS.Read more
PRP or dermal filler - Which should I choose?
People of all ages are concerned with combating various signs of skin ageing. Some of the most popular options for patients are injectables such as dermal fillers and platelet-rich plasma injections. These two are non-surgical enhancement techniques that help you look younger than your actual age.Read more
PRP treatment after hair transplantation
PRP treatment after hair transplantation is used to promote faster wound healing and hair growth after hair transplantation. PRP treatment is said to help revitalise weak hair follicles that are prone to falling out. It has been observed that the hair in the treated area is less thin and the hair shafts are thicker in patients treated with PRP.Read more
What is the effect of PRP therapy in orthopaedics?
In recent years, various methods of using platelet-rich plasma (PRP) have been applied during the treatment of various orthopaedic diseases and sports traumas. They enable the improvement of the local biological condition and the regeneration of different tissue types. PRP is a modern treatment strategy with worldwide recognition.Read more
Platelet-rich plasma: the key to PRP therapy
Platelet-rich plasma (PRP) is used in a variety of clinical applications based on the premise that higher GF content should promote better healing. Platelet derivatives represent a promising therapeutic modality and offer possibilities for the treatment of wounds, ulcers, soft tissue injuries and various other cell therapy applications.Read more
Does PRP treatment work for hair loss?
Platelet-rich plasma (PRP) is a treatment that doctors use to speed up healing in different areas of the body. It can help restore hair growth. Doctors usually use this treatment for hair loss results from androgenetic alopecia, a common condition that causes hair follicles to shrink.Read more
PRP treatment against melasma
There is no shortage of treatments to "cure" melasma, but unfortunately many of them do not work and simply rob clients of time, money and emotional stress. Platelet-rich plasma (PRP), however, offers promising treatment options for people living with melasma. Let's first discuss the disease and how PRP can help with the condition.Read more
What are PRP tubes?
Platelet-rich plasma, better known as PRP, is an autologous procedure in which a person's whole blood is drawn. The platelets are then concentrated using a centrifuge and special PRP tubes. The platelets, which contain several growth factors, are then taken again -in this feature injected into the same person makes PRP alone a very safe procedure that eliminates the likelihood of contracting communicable diseases.Read more
Photodynamic therapy (PDT)
Photodynamic therapy (PDT) is a treatment that involves light-sensitive drugs and a light source to destroy abnormal cells. It can be used to treat some skin and eye diseases as well as certain types of cancer .Read more
Lipogems / Lipogems Treatment
Lipogems is a medical device that extracts fat (also called adipose tissue) from your abdomen and injects it into your arthritic and/or painful joint. This helps relieve joint pain and allows you to regain function and return to your daily activities.Read more
PRP treatment of diabetic foot ulcers and wounds
PRP treatment of diabetic foot ulcer is effective and safe. PRP is effective if it significantly accelerates the healing of the diabetic foot ulcer and safe if it does not cause significant changes in the patient's blood haematology or blood chemistry (albumin).Read more
PRP therapy for back pain
By injecting PRP directly into the lower back, these growth factors and proteins are concentrated exactly where they are needed so they can begin to heal and repair damaged areas to relieve pain and restore normal spinal function.Read more
Platelet Rich Plasma (PRP) for brain injuries
PRP is rich in numerous growth factors associated with the repair processes following injury to the central nervous system, which consists of the brain and spinal cord.Read more
The most common sports injuries that can be treated with PRP.
Many sports injuries improve with platelet-rich plasma (PRP) injections. Both professional athletes and weekend warriors can be out due to injuries. Athletes have traditionally had the choice of either sitting out for weeks or months to heal or undergoing major surgery - neither of which is particularly desirable. PRP injections offer a radical third alternative. This minimally invasive, safe and fast orthobiological treatment is highly effective for many of the most common sports injuries.Read more
PRP in gynaecology - Vaginal rejuvenation
PRP can be extremely beneficial for vaginal rejuvenation. As platelets are responsible for both promoting healing and regenerating healthy tissues in your body, PRP can be an ideal solution if you are looking for a vaginal treatment with rejuvenating properties. Depending on your needs, PRP injections can be performed into the tissues surrounding the clitoris, urethra and G-spot. When injected into the areas targeted for treatment,Read more
PRP treatment for wrist pain
Hands and wrists are amazingly complex, with 27 bones, a complex network of ligaments, tendons, joints, nerves and muscles working gracefully together. The human hand can type across a keyboard, serve a tennis ball, turn a doorknob and feel the gentle touch of a child's hand. If you are suffering from an injury to the ligaments or tendons in your hands, wrists or elbows, a PRP injection can speed up the healing process. Your doctor may use a PRP injection with surgery to help you recover faster.Read more
Why should you offer PRP injections in your medical practice?
PRP is used in almost every field and specialty, from sports medicine to pain management, skin rejuvenation, hair care and urology. Most doctors who use this treatment also saw higher patient retention rates. So is there a legitimate reason not to add PRP to your practice?Read more
PRP (Platelet Rich Plasma) in cardiac surgery
PRP is a safe, simple and reproducible therapy that appears to offer both clinical and financial benefit to patients undergoing sternotomy for cardiac surgery. The addition of PRP to all sternal occlusions following cardiac surgery brings value by improving care and reducing costs.Read more
PRP (Platelet Rich Plasma) treatment for COPD disorders
PRP treatments for COPD conditions can help repair the air sacs or alveoli and reverse lung damage caused by smoking, pollution and other factors. Make breathing easier, relieve chest discomfort and increase stamina with PRP therapy.Read more
PRP treatment for periodontal disease
Inflammatory periodontal disease is one of the most pressing problems in dentistry, which is not only of general medical but also of social importance.Read more
PRP (Platelet Rich Plasma) therapy in dermatology
Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP therapy continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, skin augmentation and striae distensae. In addition, the combination of PRP with laser therapies, microneedling, dermal fillers and autologous fat grafting leads to synergistic effects that result in improved aesthetic outcomes.Read more
Use of PRP (Platelet Rich Plasma) therapy in dogs with pain.
Is your dog recovering from an injury or suffering from degenerative joint disease? Platelet-rich plasma therapy (PRP) can help.Read more
PRP (Platelet Rich Plasma) treatment for coccygodynia
Try PRP for coccydynia or tailbone pain, a condition for which there are no conventional remedies apart from treatments to relieve symptoms. Gain a better quality of life with the ability to sit pain-free and need support.Read more
PRP treatment for shoulder pain
In the orthopaedic community, the clinical use of PRP (platelet-rich plasma) in the treatment of shoulder pathologies has increased rapidly over the last decade.Read more
Microneedling for acne scars
As if acne is not frustrating enough, sometimes you have to deal with the scars that acne may leave. Acne scars may appear due to cystic acne or itchy skin. Like other types of scars, acne scars can last for months or longer. Even a few years. Want to learn more about microneedles for acne scars? Read on to learn more about the procedure and discuss its effectiveness and possible side effects with your dermatologist.Read more
PRP (Platelet Rich Plasma) therapy for plantar fasciitis
Recently, platelet-rich plasma (PRP) has been used as an alternative therapy for plantar fasciitis (PF) to relieve heel pain and improve functional recovery.Read more
What are platelet rich plasma (PRP) injections?
Times have changed since the days of bloodshed, when doctors treated their patients by drawing blood from them. Now a procedure called platelet-rich plasma therapy has emerged in which some of the blood is injected back into a diseased joint. You could say it's bloodshed in reverse.Read more
Does PRP therapy help with tennis elbow?
Platelet-rich plasma (PRP) therapy uses the body's own natural healing processes to repair damaged tissue. Platelets are blood cells that promote blood clotting and support wound healing. PRP contains many proteins called growth factors (more than normal blood) that help the tendon to heal and consequently relieve your pain.Read more
PRP progress: Why you as a medical professional should offer this treatment.
Platelet-rich plasma (PRP) has received considerable attention in the field of dermatology since the elucidation of its mechanism and reports of its clinical efficacy. PRP alone or in combination with other therapies has shown benefits for some cosmetic problems and skin conditions. Few transient or short-term side effects have been reported with the use of PRP. In this paper we highlight the potential efficacy and benefits of PRPRead more
PRP therapy for eye diseases
Blood products (autologous serum, platelet-rich plasma (E-PRP), plasma rich in growth factors) are successful therapies for ocular surface diseases that affect the integrity of the corneal surface and conjunctiva.Read more
PRP treatment for knee pain
Does PRP treatment work for knee pain? Platelet-rich plasma (PRP) injections are a novel treatment for pain associated with osteoarthritis of the knee.Read more
PRP treatment for erectile dysfunction
Platelet-rich plasma (PRP) found its use in the treatment of various conditions and diseases, as concentrated plasma PRP consists of many growth factors. Their interaction with surrounding cells, intracellular matrix and mediators at the injection site leads to tissue regeneration. Angiogenic, vasculogenic and regenerative effects of PRP can be used to treat erectile dysfunction (ED) and Peyronie's disease (PD).Read more
PRP injection or cortisone injection? - Which is the best option?
Before the development of PRP (platelet-rich plasma) injections, doctors generally used cortisone injections to relieve moderate to severe muscle / joint inflammation and (some) pain. However, with the creation of PRP injections, doctors can now relieve inflammation and pain as well as help the damaged tissue heal.Read more
The right care after PRP treatment
If you have PRP therapy applied as a topical serum for skin problems, your doctor will probably recommend no strenuous physical activity or exercise for about 48 to 72 hours after treatment. Recommendations may differ for other PRP applications, including orthopaedic injuries and hair loss. The best way to ensure proper healing and ideal results is to follow your provider's post-operative guidelines closely, including temporarily interrupting your exercise routine if recommended.Read more
Density Platelet Gel PRP-Kit
High-quality platelet gel PRP glass tube with separating gel and anticoagulant High Platelet Plasma (PRP) Therapy is an innovative procedure that stimulates the body’s natural healing process and uses the patient’s own cells to heal certain musculoskeletal Diseases, sports injuries and arthritis accelerate powerful growth factors to stimulate and improve blood flow in damaged areas, as well as nutrients needed for cell regeneration in damaged tissues.Read more
Treat dark circles with Vampire Lift / PRP therapy
Injecting the platelet-rich plasma under the eyes gives the skin below the eye the vital nourishment it needs. Once injected into your skin, the platelets promote the growth and regeneration of your own collagen, resulting in increased smoothness and firmness of the skin.Read more
PRP therapy for injury scars
PLATELET GROWTH FACTORS derived from blood (plasma) and responsible for repair processes can regenerate the skin in injury scars. The concentration of platelet growth factors in platelet-rich plasma (PRP) is about 95%, compared to only 4 to 5% found in normal-forming clots. Therefore, PRP can stimulate tissue regeneration much faster than normal.Read more
Wound healing through PRP therapy
Many elements such as cytokines and growth factors are involved in the regeneration process of injured tissues. The growth factors contained in platelets represent an important physiological mixture of factors that may be involved in the healing process.Read more
PRP treatment for acne
Platelet-rich plasma is injected into the acne-damaged area of the face to stimulate the production of new collagen and elastin, reduce the appearance of scars, and make the skin look brighter and smoother.Read more
Density Platelet Gel - PRP-Tubes
Density Platelet Gel - PRP tubes for your PRP treatments.Read more
PRP injection for facial beautification
Is platelet-rich plasma the secret to younger-looking skin? What exactly are PRP injections for facial beautification?Read more
PRP skin treatments
The body cells that help tissues heal and produce new cells are called platelets. PRP is injected into specific areas of the skin and then creates an environment that helps with the growth of collagen, regenerates tissue and makes your skin smooth and firm. PRP reduces wrinkles and creates a skin texture and tone that is smoother, younger and better.Read more
PRP treatment for hair loss - questions and answers
PRP therapy for hair loss is also known as platelet-rich plasma therapy . It is a treatment offered to men and women of all ethnicities. It is a simple, non-surgical procedure in which the patient's PRP is extracted by drawing blood and separating the platelet-rich plasma from the rest of the blood using a centrifuge. The plasma is then injected into the thinning areas of the scalp to stimulate hair growth and provide fuller, healthier looking hair.Read more